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(*: Wine might work on Mac, since it has a *nix OS underlying its highly-customized Mac-specific environment, though I cannot remember any Mac people ever mentioning using Wine, whereas I’ve heard plenty of Linux people mention using Wine. Linux/*nix, and thus Mac, do not natively speak Win32 there are some tools for Linux (like Wine) which allow running Win32-API-based on Linux (*), by (I believe) passing the Win32 calls through a translator to convert them to instructions that one of the GUI toolkits available on Linux can understand. Notepad++ is intimately tied to the Win32 API, which is the set of instructions, libraries, and programming philosophy behind Microsoft Windows 10 and its predecessors. Not without a complete re-write of the codebase, at which point it ceases to be Notepad++.
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